Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207461 | 0.84 | AKR1C3 (0.54) | MAOBTDP1L3MBTL1GPR52RAB9A | |
| SCHEMBL6539581 | 0.84 | AKR1C3 (0.54) | MAOBTDP1L3MBTL1GPR52RAB9A | |
| SCHEMBL6540410 | 0.84 | MAOB (0.77) | MAOBL3MBTL1GPR52RAB9ANPC1 | |
| SCHEMBL6539376 | 0.84 | MAOB (0.77) | MAOBL3MBTL1GPR52RAB9ANPC1 | |
| SCHEMBL27615709 | 0.82 | TDP1 (0.77) | TDP1L3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL8338571 | 0.82 | TDP1 (0.77) | TDP1L3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL6208279 | 0.81 | NPC1 (0.62) | TDP1L3MBTL1GPR52RAB9ANPC1 | |
| SCHEMBL8723038 | 0.79 | MAOB (0.71) | MAOBGPR52RAB9ANPC1MAPT | |
| SCHEMBL31149014 | 0.78 | RAB9A (0.49) | MAOBTDP1L3MBTL1RAB9ANPC1 | |
| SCHEMBL8716189 | 0.78 | L3MBTL1 (0.70) | MAOBTDP1L3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | MAOB 397/4885TDP1 3717/4885L3MBTL1 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.