Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147766 | 0.82 | PTGS2 (0.57) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7472447 | 0.80 | PTGS2 (0.60) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7467786 | 0.79 | PTGS2 (0.70) | PTGS2PTGS1CYP3A4CYP2C9TSHR | |
| SCHEMBL5152237 | 0.76 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5147903 | 0.75 | PTGS2 (0.52) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL5148844 | 0.74 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL6343314 | 0.73 | PTGS2 (1.00) | PTGS2PTGS1CYP3A4CYP2C9TSHR | |
| SCHEMBL7112386 | 0.70 | PTGS2 (1.00) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7468667 | 0.70 | PTGS2 (0.71) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL6166763 | 0.69 | PTGS2 (0.67) | PTGS2PTGS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116475-A1 | Pyrazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |