Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539106 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL6276970 | 0.85 | MTNR1A (0.44) | ALDH1A1MEN1KMT2AGSK3BKDM4E | |
| SCHEMBL6540424 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL6540181 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL6539762 | 0.85 | PTGS2 (0.46) | ALDH1A1MEN1KMT2AHTTGSK3B | |
| SCHEMBL6207074 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL6539157 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL6539829 | 0.83 | POLB (0.43) | ALDH1A1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL6278136 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL6539128 | 0.80 | PPARD (0.42) | ALDH1A1MEN1KMT2AHTTMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | ALDH1A1 163/4885MEN1 4420/4885KMT2A 3081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.