Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.54 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.54 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.54 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541474 | 0.83 | POLB (0.50) | POLBKMT2AALDH1A1 | |
| SCHEMBL6677132 | 0.82 | HTT (0.42) | ALKNAMPTALDH1A1 | |
| SCHEMBL6680430 | 0.81 | ALK (0.47) | ALKNAMPTKMT2A | |
| SCHEMBL6679300 | 0.80 | NLRP3 (0.42) | ALKALDH1A1 | |
| SCHEMBL6678463 | 0.80 | ABCC9 (0.54) | ABCC9ABCC8KCNJ11KCNJ8NAMPT | |
| SCHEMBL9633827 | 0.78 | MTNR1A (0.49) | ALK | |
| SCHEMBL5071533 | 0.76 | MTNR1A (0.57) | — | |
| SCHEMBL5072982 | 0.76 | POLB (0.58) | POLB | |
| SCHEMBL5073509 | 0.75 | MTNR1A (0.56) | — | |
| SCHEMBL6541431 | 0.75 | POLB (0.47) | POLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ABCC9 1823/4885ABCC8 629/4885KCNJ11 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.