Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5831376 | 0.90 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2TBXAS1EPHX2NR1H4 | |
| SCHEMBL10339161 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2GAANPSR1TBXA2R | |
| SCHEMBL6554130 | 0.81 | POLB (0.66) | GHSRELANELMNAKMT2A | |
| SCHEMBL6541466 | 0.80 | PKM (0.61) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6539832 | 0.79 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2GAANPSR1TBXA2R | |
| SCHEMBL6540943 | 0.79 | ALDH1A1 (0.73) | ALDH1A1GAANPSR1TBXA2RTBXAS1 | |
| SCHEMBL6554126 | 0.78 | POLB (0.46) | ALDH1A1GHSRELANE | |
| SCHEMBL6539185 | 0.78 | ALDH1A1 (0.68) | ALDH1A1GAANPSR1TBXA2RTBXAS1 | |
| SCHEMBL14498733 | 0.78 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2TBXAS1EPHX2NR1H4 | |
| SCHEMBL6001984 | 0.76 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2GAANPSR1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | ALDH1A1 188/4885SMN1; SMN2 2146/4885GAA 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.