Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | ELANE | P08246 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 11/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733364 | 0.89 | LMNA (0.50) | POLBMAPTPKMELANEKMT2A | |
| SCHEMBL6554126 | 0.86 | POLB (0.46) | POLBMAPTPKMELANEGHSR | |
| SCHEMBL6541466 | 0.82 | PKM (0.61) | PKMSLC6A2HTR2ASLC6A4HRH1 | |
| SCHEMBL9343618 | 0.81 | PKM (1.00) | POLBMAPTPKMELANEKMT2A | |
| SCHEMBL6540947 | 0.81 | ALDH1A1 (0.68) | ELANEKMT2AGHSRLMNA | |
| SCHEMBL9707016 | 0.78 | SLC6A2 (0.50) | POLBMAPTELANEKMT2AMEN1 | |
| SCHEMBL25596139 | 0.77 | BLM (0.47) | POLBMAPTPKMELANEKMT2A | |
| SCHEMBL6552730 | 0.77 | POLB (0.66) | POLBMAPTPKMELANEKMT2A | |
| SCHEMBL12556696 | 0.76 | LMNA (0.53) | POLBMAPTPKMELANEKMT2A | |
| SCHEMBL22033171 | 0.76 | BLM (0.63) | POLBMAPTPKMELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |