Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 3/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541137 | 1.00 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4205063 | 0.79 | ALDH1A1 (0.36) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5148517 | 0.78 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6425423 | 0.75 | HPGD (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17853170 | 0.73 | KDM4C (0.42) | SMN1; SMN2ALDH1A1KDM4EGAALPAR1 | |
| SCHEMBL17853169 | 0.71 | ALDH1A1 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5151807 | 0.71 | RORC (0.35) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5151801 | 0.71 | RORC (0.35) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3119092 | 0.71 | LPAR1 (0.38) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4204205 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDKMT2ALPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248875-A1 | Cephem compounds | ASTELLAS PHARMA INC. (JP) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248875-A1 | Cephem compounds | CEP170, C1S, SLC7A1 | NPC1 223/4885RAB9A 2742/4885SMN1; SMN2 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.