Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 5/20 | 0.37 |
| ▸ | JAK1 | P23458 | 5/20 | 0.37 |
| ▸ | TYK2 | P29597 | 5/20 | 0.37 |
| ▸ | JAK3 | P52333 | 5/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17853170 | 0.89 | KDM4C (0.42) | ALDH1A1POLBKDM4EMAPTVNN1 | |
| SCHEMBL27661737 | 0.84 | VNN1 (0.34) | ALDH1A1KDM4EHPGDMAPK1KMT2A | |
| SCHEMBL19738133 | 0.83 | RIPK2 (0.41) | ALDH1A1RIPK2PDE4BKDM4EHPGD | |
| SCHEMBL6065837 | 0.82 | LPAR1 (0.37) | ALDH1A1POLBKDM4EMAPTKMT2A | |
| SCHEMBL5494271 | 0.82 | RIPK2 (0.38) | ALDH1A1RIPK2PDE4BKDM4EHPGD | |
| SCHEMBL17853169 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL6065962 | 0.80 | LPAR1 (0.36) | RIPK2MAPTKMT2AVNN1LPAR1 | |
| SCHEMBL17853199 | 0.80 | GABRA1 (0.37) | ALDH1A1KDM4EKMT2AVNN1LPAR1 | |
| SCHEMBL6065942 | 0.80 | VNN1 (0.34) | ALDH1A1KDM4EMAPK1VNN1LPAR1 | |
| SCHEMBL3113554 | 0.78 | KCNN4 (0.37) | HPGDMAPK1VNN1LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107787324-B | Process for preparing carbamoylaminopyrazole derivatives | 桑多斯股份公司 | 2020-05-19 | — | — | CN | disclosed |
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | SANDOZ AG (CH) | 2019-07-16 | — | — | US | disclosed |
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | SANDOZ AG (CH) | 2019-07-16 | — | — | US | disclosed |
| EP-3313821-B1 | PROCESS FOR THE PREPARATION OF CARBAMOYLAMINO PYRAZOLE DERIVATIVES | SANDOZ AG (CH) | 2019-04-10 | — | — | EP | disclosed |
| US-20180305319-A1 | Process for the Preparation of Carbamoylamino Pyrazole Derivatives | SANDOZ AG (CH) | 2018-10-25 | — | — | US | disclosed |
| CN-107787324-A | Process for preparing carbamoylaminopyrazole derivatives | 桑多斯股份公司 | 2018-03-09 | — | — | CN | disclosed |
| US-20090012054-A1 | Cephem Compounds and Use as Antimicrobial Agents | ASTELLAS PHARMA INC. (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1994035-A1 | CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007119511-A1 | CEPHEM COMPOUNDS AND USE AS ANTIMICROBIAL AGENTS | ASTELLAS PHARMA INC. (JP) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351533-B2 | Process for the preparation of carbamoylamino pyrazole derivatives | PAICS, PPOX, DDC | ALDH1A1 2213/4885POLB 577/4885RIPK2 2437/4885 |
| US-20180305319-A1 | Process for the Preparation of Carbamoylamino Pyrazole Derivatives | PAICS, PPOX, DDC | ALDH1A1 2213/4885POLB 577/4885RIPK2 2437/4885 |
| US-20090012054-A1 | Cephem Compounds and Use as Antimicrobial Agents | CEP170, Q6ZSR9, H1-10 | ALDH1A1 3781/4885POLB 2296/4885RIPK2 1394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.