SCHEMBL65417

SCHEMBL65417

Cc1cn(-c2ccc(-c3ccc(-n4cc(C)c5ccccc54)cc3)cc2)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.44
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 2/20 0.44
NQO2 P16083 1/20 0.42
NR4A2 P43354 1/20 0.41
HTR6 P50406 1/20 0.41
GPR3 P46089 1/20 0.40
SCN9A Q15858 2/20 0.40
SCN2B O60939 1/20 0.40
SCN1A P35498 1/20 0.40
SCN1B Q07699 1/20 0.40
SCN5A Q14524 1/20 0.40
CYP2C9 P11712 1/20 0.39
RORC P51449 1/20 0.39
SLC6A2 P23975 1/20 0.39
ALKBH5 Q6P6C2 1/20 0.39
FTO Q9C0B1 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27522434 0.89 KDM4E (0.47) HTR7KDM4EALDH1A1NQO2NR4A2
SCHEMBL1881442 0.88 NR4A2 (0.51) HTR7KDM4EALDH1A1NQO2NR4A2
SCHEMBL20933741 0.88 CA12 (0.39) HTR7KDM4EALDH1A1NQO2NR4A2
SCHEMBL27504086 0.85 SCN2B (0.48) KDM4EALDH1A1NR4A2SCN9ASCN2B
SCHEMBL19454487 0.85 ALDH1A1 (0.59) KDM4EALDH1A1SCN9ASCN2BSCN1A
SCHEMBL9775931 0.85 FGFR1 (0.45) KDM4EALDH1A1NQO2NR4A2HTR6
SCHEMBL27529017 0.82 KIF11 (0.49) KDM4EALDH1A1HTR6SCN9ASCN2B
SCHEMBL30729432 0.82 HTT (0.50) KDM4EALDH1A1NR4A2HTR6SCN9A
SCHEMBL700645 0.81 KDM4E (0.40) KDM4EALDH1A1NQO2NR4A2HTR6
SCHEMBL19180068 0.81 NR4A2 (0.50) HTR7KDM4ENR4A2SCN9ASCN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9209417-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2015-12-08 US disclosed
US-9012034-B2 Organic electroluminescence element UDC IRELAND LIMITED (IE) 2015-04-21 US disclosed
US-8129897-B2 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8106581-B2 Organic electroluminescence element having concentration variation of hole transporting light-emitting material FUJIFILM CORPORATION (JP) 2012-01-31 US disclosed
US-20100193776-A1 ORGANIC ELECTROLUMINESCENT DEVICE UDC IRELAND LIMITED (IE) 2010-08-05 US disclosed
US-20100187985-A1 ORGANIC ELECTROLUMINESCENT DEVICE UDC IRELAND LIMITED (IE) 2010-07-29 US disclosed
US-20100123126-A1 ORGANIC ELECTROLUMINESCENT ELEMENT FUJIFILM CORPORATION (JP) 2010-05-20 US disclosed
US-7663309-B2 Organic electroluminescent element having plurality of light emitting layers with specific thicknesses FUJIFILM CORPORATION (JP) 2010-02-16 US disclosed
US-20090026938-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT UDC IRELAND LIMITED (IE) 2009-01-29 US disclosed
US-20090026940-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT UDC IRELAND LIMITED (IE) 2009-01-29 US disclosed
US-20090026939-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT UDC IRELAND LIMITED (IE) 2009-01-29 US disclosed
US-20080180023-A1 Organic electroluminescence element FUJIFILM CORPORATION 2008-07-31 US disclosed
US-20080174236-A1 Organic electroluminescence element FUJIFILM CORPORATION 2008-07-24 US disclosed
US-20080093988-A1 Organic electroluminescent element FUJIFILM CORPORATION 2008-04-24 US disclosed