SCHEMBL20933741

SCHEMBL20933741

Cc1ccccc1-c1ccc(-n2cc(C)c3ccccc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
KDM4E B2RXH2 3/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP2C9 P11712 1/20 0.38
RORC P51449 1/20 0.38
BRD4 O60885 1/20 0.38
GAA P10253 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
FTO Q9C0B1 1/20 0.38
HTR7 P34969 1/20 0.37
NR3C1 P04150 1/20 0.37
PGR P06401 1/20 0.37
POLB P06746 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
NR4A2 P43354 1/20 0.37
NQO2 P16083 1/20 0.37
HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65417 0.88 HTR7 (0.44) KDM4EALDH1A1CYP2C9RORCALKBH5
SCHEMBL27522434 0.81 KDM4E (0.47) KDM4EALDH1A1CYP2C9RORCALKBH5
SCHEMBL1881442 0.81 NR4A2 (0.51) KDM4EALDH1A1CYP2C9RORCALKBH5
SCHEMBL8172325 0.79 RORC (0.47) CYP2C9RORCHTR7SCN9A
SCHEMBL9775931 0.78 FGFR1 (0.45) KDM4EALDH1A1CYP2C9RORCGAA
SCHEMBL19454487 0.78 ALDH1A1 (0.59) KDM4EALDH1A1SCN2BSCN1ASCN1B
SCHEMBL19180068 0.78 NR4A2 (0.50) KDM4ECYP2C9RORCHTR7POLB
SCHEMBL15752310 0.78 KDM4E (0.53) CA12CA1CA2CA9KDM4E
SCHEMBL27504086 0.78 SCN2B (0.48) KDM4EALDH1A1CYP2C9RORCGAA
SCHEMBL21142509 0.76 RORC (0.38) CA12CA1CA2CA9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078461-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed