Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542821 | 0.84 | SMN1; SMN2 (0.36) | TSHRSMN1; SMN2MAPTFAAHSLC6A4 | |
| SCHEMBL11277100 | 0.76 | SLC6A4 (0.37) | SLC6A4 | |
| SCHEMBL2585984 | 0.75 | ADH1B (0.39) | TSHRSMN1; SMN2MAPTFAAHSLC6A4 | |
| SCHEMBL17887504 | 0.75 | SLC6A4 (0.39) | SLC6A4ALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL7345987 | 0.74 | ALDH1A1 (0.41) | TSHRSMN1; SMN2MAPTALDH1A1DPP4 | |
| SCHEMBL8645342 | 0.73 | ADH1B (0.47) | TSHRSMN1; SMN2MAPTFAAHSLC6A4 | |
| SCHEMBL11277200 | 0.72 | — | — | |
| SCHEMBL26008395 | 0.72 | — | — | |
| SCHEMBL11319997 | 0.72 | ADH1B (0.55) | MAPTFAAHALDH1A1FOLH1DPP4 | |
| SCHEMBL21226 | 0.71 | KMT2A (0.43) | TSHRSMN1; SMN2MAPTFOLH1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003762-B1 | BASE ANALOGUES | AMERSHAM PLC (GB) | 2004-10-13 | — | — | EP | disclosed |
| US-6605611-B2 | Nucleoside and nucleotide analogues labelled with a reporter moiety | NYCOMED AMERSHAM PLC (GB) | 2003-08-12 | — | — | US | disclosed |
| US-20030060431-A1 | Base analogues | NYCOMED AMERSHAM PLC | 2003-03-27 | — | — | US | disclosed |
| US-6444682-B1 | Base analogues | NYCOMED AMERSHAM PLC (GB) | 2002-09-03 | — | — | US | disclosed |
| EP-1003762-A2 | BASE ANALOGUES | Nycomed Amersham PLC (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999006422-A2 | BASE ANALOGUES | NYCOMED AMERSHAM PLC (GB) | 1999-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060431-A1 | Base analogues | NSUN2, XPO6, SNRPB2 | TSHR 769/4885SMN1; SMN2 489/4885MAPT 3573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.