Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8227251 | 0.84 | MAPT (0.46) | ALDH1A1MAPTLMNACYP3A4USP2 | |
| SCHEMBL8227081 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNACYP3A4USP2 | |
| SCHEMBL7345972 | 0.78 | FAAH (0.40) | ALDH1A1MAPTCYP3A4 | |
| SCHEMBL7345976 | 0.78 | FAAH (0.40) | ALDH1A1MAPTCYP3A4 | |
| SCHEMBL7340545 | 0.78 | TSHR (0.48) | ALDH1A1MAPTLMNACYP3A4USP2 | |
| SCHEMBL3126272 | 0.76 | TSHR (0.43) | ALDH1A1MAPTLMNACYP3A4USP2 | |
| SCHEMBL3115628 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNACYP3A4USP2 | |
| Urea SCHEMBL11092787 | 0.74 | MAPT (0.45) | ALDH1A1MAPTLMNACYP3A4USP2 | |
| SCHEMBL3111804 | 0.74 | TSHR (0.46) | ALDH1A1MAPTLMNACYP3A4USP2 | |
| SCHEMBL6542832 | 0.74 | TSHR (0.37) | ALDH1A1MAPTLMNACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4639468-A | Derivatives of glycinamide, their preparation and their use | CONTINENTAL PHARMA INC. (BE) | 1987-01-27 | — | — | US | disclosed |