SCHEMBL6542875

SCHEMBL6542875

C=CC(O)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5139541 0.82
SCHEMBL649043 0.72
SCHEMBL33041 0.70
SCHEMBL78668 0.70
SCHEMBL8665784 0.68
SCHEMBL22618954 0.68
SCHEMBL1501604 0.67
Fluoride SCHEMBL25175826 0.67
SCHEMBL1705892 0.67
Hydrogen Sulfide SCHEMBL5636795 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900654-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES Sumitomo Chemical Company Limited (JP) 2015-08-05 EP disclosed
EP-2900655-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2015-08-05 EP disclosed
EP-2841429-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
WO-2013162072-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-31 WO disclosed
EP-1282413-A4 HALOGENATED 2-AMINO-5,6 HEPTENOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS PHARMACIA CORP (US) 2004-12-01 EP disclosed
EP-1282413-A1 HALOGENATED 2-AMINO-5,6 HEPTENOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS Pharmacia Corporation (US) 2003-02-12 EP disclosed
US-6465686-B2 ADMINISTERING HALOGENATED AMIDINO OR OXYAMIDINO COMPOUND TO TREAT DISEASES CAUSED BY NITRIC OXIDE SYNTHASE PHARMACIA CORPORATION 2002-10-15 US disclosed
US-20020049202-A1 Halogenated 2-amino-5,6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors GRAPPERHAUS MARGARET L (US) 2002-04-25 US disclosed
WO-2001078719-A1 HALOGENTATED 2-AMINO-5,6 HEPTENOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS PHARMACIA CORPORATION (US) 2001-10-25 WO disclosed