Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.51 |
| ▸ | PPARA | Q07869 | 8/20 | 0.51 |
| ▸ | PPARD | Q03181 | 5/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009638 | 0.89 | PPARG (0.50) | PPARGPPARAPPARDADRB3ALDH1A1 | |
| SCHEMBL6543048 | 0.87 | PPARG (0.48) | PPARGPPARAPPARDALDH1A1KDM4E | |
| SCHEMBL6543944 | 0.87 | PPARG (0.54) | PPARGPPARAPPARDADRB3KDM4E | |
| SCHEMBL6543024 | 0.86 | PPARA (0.49) | PPARGPPARAPPARDADRB3ALDH1A1 | |
| SCHEMBL1009685 | 0.85 | PPARG (0.54) | PPARGPPARAPPARDADRB3KDM4E | |
| SCHEMBL6544050 | 0.82 | PPARG (0.56) | PPARGPPARAPPARDADRB3KDM4E | |
| SCHEMBL6543121 | 0.81 | PPARG (0.51) | PPARGPPARAPPARDADRB3ALDH1A1 | |
| SCHEMBL1009987 | 0.81 | PPARA (0.48) | PPARGPPARAPPARDALDH1A1KDM4E | |
| SCHEMBL1010612 | 0.80 | PPARA (0.56) | PPARGPPARAPPARDADRB3 | |
| SCHEMBL1010866 | 0.80 | ADRB3 (0.52) | PPARGPPARAPPARDADRB3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |