Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.56 |
| ▸ | PPARA | Q07869 | 12/20 | 0.56 |
| ▸ | PPARD | Q03181 | 8/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543944 | 0.95 | PPARG (0.54) | PPARGPPARAPPARDKCNH2ADRB3 | |
| SCHEMBL6543121 | 0.91 | PPARG (0.51) | PPARGPPARAPPARDADRB3 | |
| SCHEMBL6544135 | 0.85 | ADRB3 (0.56) | PPARGPPARAPPARDADRB3KDM4E | |
| SCHEMBL6543048 | 0.85 | PPARG (0.48) | PPARGPPARAPPARDKDM4EMAPT | |
| SCHEMBL6544252 | 0.85 | PPARG (0.62) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL1010612 | 0.85 | PPARA (0.56) | PPARGPPARAPPARDADRB3CYP4F2 | |
| SCHEMBL6542914 | 0.85 | PPARG (0.47) | PPARGPPARAPPARDADRB3MAPT | |
| SCHEMBL6544098 | 0.84 | PPARG (0.61) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL6544255 | 0.84 | PPARG (0.55) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL6543074 | 0.84 | PPARG (0.39) | PPARGPPARAPPARDKCNH2ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |