Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.51 |
| ▸ | PPARA | Q07869 | 9/20 | 0.51 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543048 | 0.94 | PPARG (0.48) | PPARGPPARAPPARDP2RY14ALDH1A1 | |
| SCHEMBL6542914 | 0.94 | PPARG (0.47) | PPARGPPARAPPARDADRB3 | |
| SCHEMBL6543944 | 0.92 | PPARG (0.54) | PPARGPPARAPPARDADRB3P2RY14 | |
| SCHEMBL6544050 | 0.91 | PPARG (0.56) | PPARGPPARAPPARDADRB3 | |
| SCHEMBL6543126 | 0.90 | PPARA (0.50) | PPARGPPARAPPARDADRB3 | |
| SCHEMBL1009457 | 0.89 | PPARA (0.51) | PPARGPPARAPPARDP2RY14ALDH1A1 | |
| SCHEMBL2440050 | 0.86 | PPARD (0.51) | PPARGPPARAPPARDBCHEADRB3 | |
| SCHEMBL6544153 | 0.85 | PPARA (0.49) | PPARGPPARAPPARDBCHEALDH1A1 | |
| SCHEMBL1012221 | 0.84 | PPARA (0.47) | PPARGPPARAPPARDP2RY14 | |
| SCHEMBL6544120 | 0.84 | PPARA (0.47) | PPARGPPARAPPARDP2RY14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |