Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | VNN1 | O95497 | 4/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871444 | 0.88 | PKM (0.58) | ALDH1A1KDM4EHPGDKMT2AKDR | |
| SCHEMBL6542710 | 0.86 | KDR (0.62) | ALDH1A1KDRBDKRB1 | |
| SCHEMBL3714863 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL31204910 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL18071001 | 0.82 | MAPT (0.65) | ALDH1A1KDM4EKMT2AKDRBDKRB1 | |
| SCHEMBL7823349 | 0.82 | KDR (0.60) | ALDH1A1KDM4EHPGDKDRBDKRB1 | |
| SCHEMBL6543897 | 0.81 | BDKRB1 (0.51) | ALDH1A1KDM4EHPGDKDRBDKRB1 | |
| Hydrochloric Acid SCHEMBL7832291 | 0.81 | KDR (0.59) | ALDH1A1KDM4EHPGDKDRBDKRB1 | |
| SCHEMBL2381269 | 0.80 | KDM4E (0.62) | ALDH1A1KDM4EHPGDTSHRKMT2A | |
| SCHEMBL18432805 | 0.80 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040254185-A1 | Selective anthranilamide pyridine amides as inhibitors of vegfr-2 and vegfr-3 | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-12-16 | — | — | US | disclosed |
| CN-1518546-A | Selective anthranilamide picolinamides as VEGRF-2 and VEGFR-3 inhibitors | ���ֹɷݹ�˾ | 2004-08-04 | — | — | CN | disclosed |
| EP-1392680-A2 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002090352-A2 | SELECTIVE ANTHRANILAMIDE PYRIDINE AMIDES AS INHIBITORS OF VEGFR-2 AND VEGFR-3 | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254185-A1 | Selective anthranilamide pyridine amides as inhibitors of vegfr-2 and vegfr-3 | FLT4, KDR, FLT1 | ALDH1A1 2140/4885KDM4E 831/4885HPGD 2323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.