Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | BDKRB1 | P46663 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542710 | 0.90 | KDR (0.62) | BDKRB1ALDH1A1KDR | |
| SCHEMBL18071001 | 0.88 | MAPT (0.65) | BDKRB1ALDH1A1KDM4EKDRMAPT | |
| SCHEMBL6542903 | 0.88 | ALDH1A1 (0.58) | BDKRB1ALDH1A1HPGDKDM4EKDR | |
| SCHEMBL2087990 | 0.88 | HTT (0.65) | L3MBTL1ALDH1A1KDM4EKDRMAPT | |
| SCHEMBL7823349 | 0.88 | KDR (0.60) | L3MBTL1BDKRB1ALDH1A1HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL7832291 | 0.87 | KDR (0.59) | L3MBTL1BDKRB1ALDH1A1HPGDKDM4E | |
| SCHEMBL6168145 | 0.85 | KDM5B (0.66) | ALDH1A1KDM4EKDRTDP1KDM5B | |
| SCHEMBL20722727 | 0.82 | KDM4E (0.62) | ALDH1A1HPGDKDM4EKDRTDP1 | |
| SCHEMBL7109846 | 0.82 | KDR (0.55) | KDM4EKDRTDP1KDM5BMAPT | |
| SCHEMBL11492008 | 0.82 | KDM4E (0.54) | PKML3MBTL1BDKRB1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-7071187-B2 | Naphthyridine derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2006-07-04 | — | — | US | disclosed |
| US-20040214853-A1 | Naphthyridine derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1426374-A1 | NAPHTHYRIDINE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2004-06-09 | — | — | EP | disclosed |
| EP-0784622-B1 | NAPHTHYRIDINONE DERIVATIVES | KNOLL GMBH (DE) | 2001-11-21 | — | — | EP | disclosed |
| US-5854257-A | Naphthyridinone derivatives | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-12-29 | — | — | US | disclosed |
| EP-0784622-A1 | NAPHTHYRIDINONE DERIVATIVES | Knoll AG (DE) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011199-A1 | NAPHTHYRIDINONE DERIVATIVES | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214853-A1 | Naphthyridine derivatives | MT-ND1, OPRD1, NR0B1 | PKM 2964/4885L3MBTL1 1727/4885BDKRB1 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.