Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.48 |
| ▸ | HRH2 | P25021 | 6/20 | 0.48 |
| ▸ | HRH1 | P35367 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833294 | 0.88 | RAB9A (0.61) | RAB9AMAPTSMN1; SMN2MMP2MMP3 | |
| SCHEMBL6740077 | 0.88 | RAB9A (0.72) | RAB9AMAPTSMN1; SMN2MMP2MMP3 | |
| SCHEMBL8484092 | 0.84 | RAB9A (0.66) | RAB9AMAPTSMN1; SMN2MMP2MMP3 | |
| SCHEMBL3922051 | 0.81 | HPGD (0.70) | RAB9AMAPTSMN1; SMN2MMP2MMP3 | |
| SCHEMBL7213277 | 0.81 | RAB9A (0.69) | RAB9AMAPTSMN1; SMN2HRH3HPGD | |
| SCHEMBL10674350 | 0.80 | RAB9A (0.82) | RAB9AMAPTSMN1; SMN2MMP2MMP3 | |
| SCHEMBL10075064 | 0.78 | RAB9A (0.49) | RAB9AMAPTSMN1; SMN2MMP2MMP3 | |
| SCHEMBL950598 | 0.77 | HPGD (0.59) | RAB9AMAPTSMN1; SMN2MMP2MMP3 | |
| SCHEMBL6542880 | 0.77 | RAB9A (0.65) | RAB9AMAPTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL11920128 | 0.77 | RAB9A (0.63) | RAB9AMAPTSMN1; SMN2HRH1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730242-B2 | EFFICIENCY | THE UNIVERSITY OF ROCHESTER | 2004-05-04 | — | — | US | disclosed |
| US-20030164473-A1 | Glass-forming liquid crystalline compositions and optical devices formed therefrom | NATIONAL SCIENCE FOUNDATION | 2003-09-04 | — | — | US | disclosed |
| US-6558572-B2 | Optical device | UNIVERSITY OF ROCHESTER | 2003-05-06 | — | — | US | disclosed |
| US-20010036517-A1 | Glass-forming liquid crystalline compositions and optical devices formed therefrom | NATIONAL SCIENCE FOUNDATION | 2001-11-01 | — | — | US | disclosed |