Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922051 | 0.92 | HPGD (0.70) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL6740077 | 0.87 | RAB9A (0.72) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL8484092 | 0.86 | RAB9A (0.66) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL8553437 | 0.86 | RAB9A (0.73) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL8050007 | 0.86 | RAB9A (0.73) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL8833294 | 0.83 | RAB9A (0.61) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL4728037 | 0.81 | HPGD (0.59) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL25042262 | 0.81 | HPGD (0.58) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL30274227 | 0.81 | HPGD (0.58) | HPGDNPSR1RAB9ANPC1MAPT | |
| SCHEMBL25042562 | 0.81 | HPGD (0.58) | HPGDNPSR1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008985-A2 | METHODS AND COMPOSITIONS FOR IMPROVED DELIVERY OF THERAPEUTIC AND DIAGNOSTIC AGENTS | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-20 | — | — | WO | disclosed |