Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543517 | 0.94 | PPARA (0.46) | PPARACYSLTR2CYSLTR1PTGDR2FFAR1 | |
| SCHEMBL1010192 | 0.89 | PPARA (0.49) | PPARACYSLTR2CYSLTR1FFAR1PTPN1 | |
| SCHEMBL2440050 | 0.86 | PPARD (0.51) | PPARABCHEALDH1A1L3MBTL1PPARG | |
| SCHEMBL2441911 | 0.85 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL6543121 | 0.85 | PPARG (0.51) | PPARABCHEALDH1A1L3MBTL1PPARG | |
| SCHEMBL1011009 | 0.82 | PPARA (0.43) | PPARAPTGIRPPARGPPARD | |
| SCHEMBL2439070 | 0.81 | PPARG (0.47) | PPARAPTPN1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL6543048 | 0.80 | PPARG (0.48) | PPARAPTPN1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL2437822 | 0.80 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL6542914 | 0.79 | PPARG (0.47) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |