Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543070 | 0.88 | POLB (0.55) | POLBEPHX2SIGMAR1CYP1A2CYP3A4 | |
| SCHEMBL6542960 | 0.83 | TAAR1 (0.56) | EPHX2PPARGPPARASMN1; SMN2MEN1 | |
| SCHEMBL30768879 | 0.83 | POLB (0.80) | POLBEPHX2SIGMAR1CYP1A2CYP3A4 | |
| SCHEMBL2436610 | 0.79 | PPARA (0.51) | SIGMAR1PPARGPPARAMEN1KMT2A | |
| SCHEMBL11215916 | 0.79 | PPARG (0.61) | PPARGPPARACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL5795203 | 0.78 | PPARG (0.64) | PPARGPPARACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1800332 | 0.77 | EPHX2 (0.74) | POLBEPHX2SIGMAR1MEN1KMT2A | |
| SCHEMBL17896307 | 0.76 | EPHX2 (0.63) | POLBEPHX2SIGMAR1SMN1; SMN2MEN1 | |
| SCHEMBL7248386 | 0.76 | PPARG (0.61) | PPARGPPARACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL3397254 | 0.75 | EPHX2 (1.00) | POLBEPHX2SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |