Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.51 |
| ▸ | BCL9 | O00512 | 5/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436874 | 0.81 | MEN1 (0.58) | BCL9CTNNB1HDAC6MEN1KMT2A | |
| SCHEMBL6543337 | 0.79 | POLB (0.58) | PPARAPPARGALDH1A1MEN1KMT2A | |
| SCHEMBL6542960 | 0.78 | TAAR1 (0.56) | PPARAPPARGBCL9CTNNB1ALDH1A1 | |
| SCHEMBL12953654 | 0.76 | KMT2A (0.58) | PPARAPPARGALDH1A1MEN1KMT2A | |
| SCHEMBL7946795 | 0.75 | GLS (0.48) | HDAC6NPC1RAB9A | |
| SCHEMBL12953910 | 0.75 | KDM4E (0.59) | PPARAPPARGALDH1A1MEN1KMT2A | |
| SCHEMBL3125633 | 0.75 | NPC1 (0.57) | HDAC6MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2436611 | 0.74 | BCL9 (0.49) | PPARAPPARGBCL9CTNNB1 | |
| SCHEMBL5795203 | 0.73 | PPARG (0.64) | PPARAPPARGMEN1KMT2APPARD | |
| SCHEMBL12953991 | 0.73 | PPARA (0.59) | PPARAPPARGALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |