Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517001 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL25159 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL28117044 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL6689612 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL6483432 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL5353745 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL1954690 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL12761516 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| Bicarbonate SCHEMBL4901524 | 0.93 | LMNA (0.58) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL28002029 | 0.93 | KDM4E (0.58) | KDM4ELMNAADRA2CADRA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815566-B2 | USING OSMIUM COMPOUND ON CATALYST SUPPORT | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-11-09 | — | — | US | disclosed |
| EP-1209142-B1 | Preparation of new layered double hydroxides exchanged with osmate for asymmetric dihydroxylation of olefins to vicinal diols | COUNCIL SCIENT IND RES (IN) | 2004-05-26 | — | — | EP | disclosed |
| US-6703531-B2 | PROCESS FOR THE ASYMMETRIC DIHYDROXYLATION OF OLEFINS TO OBTAIN VICINAL DIOLS USING A NOVEL HETEROGENEOUS SUPPORTED OSMATE OF THE INVENTION. | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-03-09 | — | — | US | disclosed |
| EP-1175379-B1 | METHOD FOR THE ASYMMETRIC DIHYDROXYLATION OF OLEFINS, USING OSMIUM CATALYSTS | BAYER CHEMICALS AG (DE) | 2004-01-02 | — | — | EP | disclosed |
| US-20030212300-A1 | Supported osmates, process for preparation thereof, and a process for the preparation of chiral vicinal diols using supported osmate catalyst | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2003-11-13 | — | — | US | disclosed |
| US-6646168-B2 | Assymmetric dihydroxylating olefins using cinchona alkaloid, oxidant and quaternary amine osmium oxide catalyst | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-11-11 | — | — | US | disclosed |
| WO-2003080242-A1 | SUPPORTED OSMATES, PROCESS FOR PREPARATION THEREOF, AND PROCESS FOR PREPARATION OF CHIRAL VICINAL DIOLS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-10-02 | — | — | WO | disclosed |
| US-20030153794-A1 | Process for the preparation of supported osmates | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH. | 2003-08-14 | — | — | US | disclosed |
| US-20030105367-A1 | Supported osmates, process for preparation thereof, and a process for the preparation of chiral vicinal diols using supported osmate catalyst | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-06-05 | — | — | US | disclosed |
| WO-2003035253-A1 | PROCESS FOR THE PREPARATION OF SUPPORTED OSMATES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-05-01 | — | — | WO | disclosed |
| US-6552234-B1 | Reacting potassium osmate with such as quaternary ammonium divinylbenzene-styrene copolymer | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-04-22 | — | — | US | disclosed |
| US-6472570-B1 | Method for the asymmetric dihydroxylation of olefins, using osmium catalysts | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |
| EP-1209142-A1 | Preparation of new layered double hydroxides exchanged with osmate for asymmetric dihydroxylation of olefins to vicinal diols | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-05-29 | — | — | EP | disclosed |
| US-6387033-B1 | CIS ISOMERS FOR HYDROXYLATION OF OLEFINS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-05-14 | — | — | US | disclosed |
| EP-1175379-A1 | METHOD FOR THE ASYMMETRIC DIHYDROXYLATION OF OLEFINS, USING OSMIUM CATALYSTS | Bayer Aktiengesellschaft (DE) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000064844-A1 | METHOD FOR THE ASYMMETRIC DIHYDROXYLATION OF OLEFINS, USING OSMIUM CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-02 | — | — | WO | disclosed |