Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517001 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL25159 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL6543382 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL28117044 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL6689612 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL6483432 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL1954690 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL12761516 | 1.00 | KDM4E (0.65) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| Bicarbonate SCHEMBL4901524 | 0.93 | LMNA (0.58) | KDM4ELMNAADRA2CADRA2AHIF1A | |
| SCHEMBL28002029 | 0.93 | KDM4E (0.58) | KDM4ELMNAADRA2CADRA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9000280-A | — | — | None | — | — | JP | disclosed |
| US-20160097063-A1 | Production Of Enantiopure alpha-Hydroxy Carboxylic Acids From Alkenes By Cascade Biocatalysis | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-04-07 | — | — | US | disclosed |
| US-20160097063-A1 | Production Of Enantiopure alpha-Hydroxy Carboxylic Acids From Alkenes By Cascade Biocatalysis | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-04-07 | — | — | US | disclosed |
| US-7166749-B2 | Process for preparing chiral aromatic α-hydroxy ketones using 2-hydroxy-3-oxoacid synthase | BEN-GURION UNIVERSITY OF THE NEGEV (IL) | 2007-01-23 | — | — | US | disclosed |
| EP-1468101-B1 | PROCESS FOR PREPARING CHIRAL AROMATIC ALPHA-HYDROXY KETONES USING 2-HYDROXY-3-OXOACID SYNTHASE | UNIV BEN GURION (IL) | 2006-11-22 | — | — | EP | disclosed |
| US-20060148042-A1 | Process for preparing chiral aromatic alpha-hydroxy ketones using 2-hydroxy-3-oxoacid synthase | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2006-07-06 | — | — | US | disclosed |
| JP-H09280-A | PRODUCTION OF (1R,2S)-1-PHENYL-1,2-PROPANEDIOL | ASAHI BREWERIES LTD | 1997-01-07 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148042-A1 | Process for preparing chiral aromatic alpha-hydroxy ketones using 2-hydroxy-3-oxoacid synthase | CYP2S1, ACSS2, ADSS2 | KDM4E 1771/4885LMNA 3483/4885ADRA2C 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.