Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19277770 | 0.87 | MAPT (0.65) | EPHX1KMT2AHTTALDH1A1MEN1 | |
| SCHEMBL29451289 | 0.84 | SMN1; SMN2 (0.66) | KMT2AALDH1A1MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6579496 | 0.84 | SMN1; SMN2 (0.66) | KMT2AALDH1A1MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28918511 | 0.83 | SMN1; SMN2 (0.64) | KMT2AALDH1A1MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL16119683 | 0.82 | EPHX1 (0.81) | EPHX1KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL1191054 | 0.80 | ALDH1A1 (0.58) | EPHX1KMT2AHTTALDH1A1MEN1 | |
| SCHEMBL862532 | 0.79 | TSHR (0.70) | KMT2AALDH1A1MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11660382 | 0.79 | HPGD (0.70) | KMT2AHTTALDH1A1MEN1L3MBTL1 | |
| SCHEMBL5446889 | 0.79 | GAA (0.81) | EPHX1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL9018859 | 0.78 | KMT2A (0.60) | KMT2AHTTALDH1A1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806282-B2 | HAVE AN ANTAGONISTIC ACTIVITY WITH RESPECT TO CORTICOTROPIN RELEASING FACTOR | SANOFI-SYNTHELABO (FR) | 2004-10-19 | — | — | US | disclosed |
| EP-1242389-B1 | NOVEL BRANCHED SUBSTITUTED AMINO DERIVATIVES OF 3-AMINO-1-PHENYL-1H[1,2,4]TRIAZOL, METHODS FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI SYNTHELABO (FR) | 2004-04-21 | — | — | EP | disclosed |
| US-20030162771-A1 | Novel branched substituted amino derivatives of 3-amino-1-phenyl-1h-[1,2,4] triazol, methods for producing them and pharmaceutical compositions containing them | SANOFI (FR) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162771-A1 | Novel branched substituted amino derivatives of 3-amino-1-phenyl-1h-[1,2,4] triazol, methods for producing them and pharmaceutical compositions containing them | CRHR1, ADRA2C, NPY1R | EPHX1 3260/4885KMT2A 3493/4885HTT 4601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.