Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 8/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30593474 | 1.00 | KDM4E (0.64) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL30641650 | 1.00 | KDM4E (0.64) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL27174137 | 0.84 | KMT2A (0.58) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL148991 | 0.84 | KMT2A (0.58) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL29625837 | 0.84 | KMT2A (0.58) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| Triphenylene SCHEMBL29177920 | 0.82 | KMT2A (0.56) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL6845282 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL570295 | 0.80 | KMT2A (0.47) | KDM4EALDH1A1MAOAHPGDSMN1; SMN2 | |
| SCHEMBL653724 | 0.80 | RAB9A (0.62) | KDM4EALDH1A1MAOAGLACYP3A4 | |
| SCHEMBL2532507 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1MAOAGLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4623648-A | 1-azaxanthone for use as therapeutic agent as an antipyretic, analgesic, anti-inflammatory and bronchodilator | LACER, S.A. (ES) | 1986-11-18 | — | — | US | claimed |
| EP-0075607-B1 | 1-AZAXANTHONE FOR USE AS THERAPEUTIC AGENT, PROCESSES FOR ITS PRODUCTION AND PHARMACEUTICAL COMPOSITIONS | LACER, S.A. (ES) | 1985-03-13 | — | — | EP | claimed |
| EP-0075607-A1 | 1-Azaxanthone for use as therapeutic agent, processes for its production and pharmaceutical compositions | LACER, S.A. (ES) | 1983-04-06 | — | — | EP | claimed |
| JP-53111097-A | — | — | None | — | — | JP | disclosed |
| JP-54088298-A | — | — | None | — | — | JP | disclosed |
| US-20240366652-A1 | OSTEOARTHRITIS PROGRESSION INHIBITOR AND PROGRESSION INHIBITION KIT | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2024-11-07 | — | — | US | disclosed |
| EP-4400110-A1 | OSTEOARTHRITIS PROGRESSION INHIBITOR AND PROGRESSION INHIBITION KIT | Kyushu University, National University Corporation (JP) | 2024-07-17 | — | — | EP | disclosed |
| CN-118345390-A | Method for preparing carbonyl compound by electrocatalytic oxidation of benzyl C-H bond by pyridine nitrogen oxide | 浙江大学 | 2024-07-16 | — | — | CN | disclosed |
| EP-3635056-B1 | LIGHT COLOR ROSIN ESTER COMPOSITIONS AND METHODS OF MAKING SAME | KRATON POLYMERS LLC (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-111349397-B | Pale rosin and rosin ester compositions | 科腾聚合物有限责任公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2023033151-A1 | OSTEOARTHRITIS PROGRESSION INHIBITOR AND PROGRESSION INHIBITION KIT | 国立大学法人九州大学 | 2023-03-09 | — | — | WO | disclosed |
| EP-0075607-A1 | 1-Azaxanthone for use as therapeutic agent, processes for its production and pharmaceutical compositions | LACER, S.A. (ES) | 1983-04-06 | — | — | EP | disclosed |
| EP-0075607-A1 | 1-Azaxanthone for use as therapeutic agent, processes for its production and pharmaceutical compositions | LACER, S.A. (ES) | 1983-04-06 | — | — | EP | disclosed |
| EP-0075607-A1 | 1-Azaxanthone for use as therapeutic agent, processes for its production and pharmaceutical compositions | LACER, S.A. (ES) | 1983-04-06 | — | — | EP | disclosed |
| US-4299963-A | ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| JP-S5488298-A | PRODUCTION OF 1-AZAXANTHONE DERIVATIVE | TAKEDA CHEM IND LTD | 1979-07-13 | — | — | JP | disclosed |
| JP-S53111097-A | 1-AZAXANTHONE DERIVATIVE AND ITS PREPARATION | TAKEDA CHEM IND LTD | 1978-09-28 | — | — | JP | disclosed |
| JP-S05488298-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240366652-A1 | OSTEOARTHRITIS PROGRESSION INHIBITOR AND PROGRESSION INHIBITION KIT | GRK5, KIT, MRGPRX2 | KDM4E 1726/4885ALDH1A1 1317/4885MAOA 2897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.