Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20680503 | 0.78 | LMNA (0.38) | LMNAALDH1A1THRB | |
| SCHEMBL6543885 | 0.73 | — | — | |
| SCHEMBL2441992 | 0.73 | — | — | |
| Glycerin SCHEMBL9439059 | 0.71 | LMNA (1.00) | LMNAALDH1A1THRBTDP1MAPT | |
| Glycerin SCHEMBL14278795 | 0.71 | — | — | |
| Glycerin SCHEMBL8080917 | 0.71 | LMNA (1.00) | LMNAALDH1A1THRBTDP1MAPT | |
| Glycerin SCHEMBL797 | 0.71 | — | — | |
| Glycerin SCHEMBL14278797 | 0.71 | — | — | |
| Glycerin SCHEMBL3418854 | 0.71 | LMNA (1.00) | LMNAALDH1A1THRBTDP1MAPT | |
| Glycerin SCHEMBL5610362 | 0.71 | LMNA (1.00) | LMNAALDH1A1THRBTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509533-B1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | UNIV MCMASTER (CA) | 2009-10-21 | — | — | EP | claimed |
| WO-2008061363-A1 | BIOMOLECULE COMPATIBLE SILICA PARTICLES | MCMASTER UNIVERSITY (CA) | 2008-05-29 | — | — | WO | claimed |
| US-20070207484-A1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | MCMASTER UNIVERSITY (CA) | 2007-09-06 | — | — | US | claimed |
| EP-1509533-A1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | McMASTER UNIVERSITY (CA) | 2005-03-02 | — | — | EP | claimed |
| US-20040034203-A1 | Polyol-modified silanes as precursors for silica | MCMASTER UNIVERSITY (CA) | 2004-02-19 | — | — | US | claimed |
| WO-2003102001-A1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | MCMASTER UNIVERSITY (CA) | 2003-12-11 | — | — | WO | claimed |
| EP-1509533-B1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | UNIV MCMASTER (CA) | 2009-10-21 | — | — | EP | disclosed |
| WO-2008061363-A1 | BIOMOLECULE COMPATIBLE SILICA PARTICLES | MCMASTER UNIVERSITY (CA) | 2008-05-29 | — | — | WO | disclosed |
| US-20070207484-A1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | MCMASTER UNIVERSITY (CA) | 2007-09-06 | — | — | US | disclosed |
| EP-1509533-A1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | McMASTER UNIVERSITY (CA) | 2005-03-02 | — | — | EP | disclosed |
| US-20040034203-A1 | Polyol-modified silanes as precursors for silica | MCMASTER UNIVERSITY (CA) | 2004-02-19 | — | — | US | disclosed |
| WO-2003102001-A1 | POLYOL-MODIFIED SILANES AS PRECURSORS FOR SILICA | MCMASTER UNIVERSITY (CA) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034203-A1 | Polyol-modified silanes as precursors for silica | SUGT1, SORD, UGCG | LMNA 1981/4885ALDH1A1 2717/4885THRB 4315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.