Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6754002 | 0.96 | NPC1 (0.57) | MPLNPC1RAB9AGAAHDAC6 | |
| SCHEMBL6759177 | 0.94 | NPC1 (0.55) | MPLNPC1RAB9AGAAHDAC6 | |
| SCHEMBL3334877 | 0.84 | NPC1 (0.66) | NPC1RAB9AGAAHDAC6KDM4E | |
| SCHEMBL9295731 | 0.84 | MPL (0.67) | MPLNPC1RAB9AGAAHDAC6 | |
| SCHEMBL9295726 | 0.84 | MPL (0.57) | MPLNPC1RAB9AHDAC6HDAC3 | |
| SCHEMBL9095200 | 0.83 | MPL (0.63) | MPLNPC1RAB9AGAAHDAC6 | |
| SCHEMBL9095196 | 0.83 | MPL (0.54) | MPLNPC1RAB9AGAAHDAC6 | |
| SCHEMBL4702843 | 0.82 | NPC1 (0.69) | NPC1RAB9AGAAHDAC6KDM4E | |
| SCHEMBL21976964 | 0.82 | MPL (0.65) | MPLNPC1RAB9AHDAC6HDAC3 | |
| SCHEMBL11453513 | 0.81 | NPC1 (0.51) | NPC1RAB9AHDAC6KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10894802-B2 | Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same | YALE UNIVERSITY (US) | 2021-01-19 | — | — | US | disclosed |
| US-20170305948-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | UNIV YALE (US) | 2017-10-26 | — | — | US | disclosed |
| US-20040171264-A1 | Methods of polishing, interconnect-fabrication, and producing semiconductor devices | RENESAS TECHNOLOGY CORPORATION | 2004-09-02 | — | — | US | disclosed |
| US-6750128-B2 | Methods of polishing, interconnect-fabrication, and producing semiconductor devices | RENESAS TECHNOLOGY CORPORATION (JP) | 2004-06-15 | — | — | US | disclosed |
| US-6712262-B2 | BENZIMIDAZOLE AND IODINE COMPOUNDS | TAMURAKAKEN CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |
| US-20030186497-A1 | Methods of polishing, interconnect-fabrication, and producing semiconductor devices | HITACHI, LTD. | 2003-10-02 | — | — | US | disclosed |
| US-6562719-B2 | Methods of polishing, interconnect-fabrication, and producing semiconductor devices | HITACHI, LTD. (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20020016073-A1 | Methods of polishing, interconnect-fabrication, and producing semiconductor devices | HITACHI, LTD. | 2002-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305948-A1 | NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME | TIMCC, YAP1, TET2 | MPL 2216/4885NPC1 4247/4885RAB9A 2943/4885 |
| US-10894802-B2 | Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same | TIMCC, YAP1, TET2 | MPL 2421/4885NPC1 3836/4885RAB9A 3083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.