Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.55 |
| ▸ | MPL | P40238 | 1/20 | 0.55 |
| ▸ | ATP4A | P20648 | 1/20 | 0.55 |
| ▸ | ATP4B | P51164 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759177 | 0.99 | NPC1 (0.55) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL6544064 | 0.96 | MPL (0.59) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL3334877 | 0.83 | NPC1 (0.66) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL4702843 | 0.81 | NPC1 (0.69) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL5141117 | 0.81 | ATP4A (0.76) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9320573 | 0.80 | ATP4A (0.74) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9295731 | 0.79 | MPL (0.67) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL9295726 | 0.79 | MPL (0.57) | NPC1RAB9ASMN1; SMN2TP53MPL | |
| SCHEMBL29386825 | 0.79 | NPC1 (0.88) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL2178266 | 0.79 | NPC1 (0.88) | NPC1RAB9AGAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6712262-B2 | BENZIMIDAZOLE AND IODINE COMPOUNDS | TAMURAKAKEN CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |