Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 3/20 | 0.61 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.61 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544636 | 0.93 | GABBR2 (0.64) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL6544656 | 0.88 | GABBR2 (0.64) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL11420819 | 0.87 | TSHR (0.43) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL29919399 | 0.85 | TSHR (0.41) | GABBR2GABBR1GABRR1LMNATSHR | |
| SCHEMBL341290 | 0.80 | — | — | |
| Phosphoric Acid SCHEMBL27508186 | 0.79 | LMNA (0.50) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL6351264 | 0.79 | GABBR2 (0.87) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL6358928 | 0.77 | GABBR2 (0.83) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL6360412 | 0.77 | GABBR2 (0.83) | GABBR2GABBR1GABRR1LMNABLM | |
| SCHEMBL6354602 | 0.77 | GABBR2 (0.83) | GABBR2GABBR1GABRR1LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372620-A2 | METHODS FOR RESTORING COGNITIVE FUNCTION FOLLOWING SYSTEMIC STRESS | Saegis Pharmaceuticals (US) | 2004-01-02 | — | — | EP | claimed |
| WO-2002074293-A2 | METHODS FOR RESTORING COGNITIVE FUNCTION FOLLOWING SYSTEMIC STRESS | SAEGIS PHARMACEUTICALS INC (US) | 2002-09-26 | — | — | WO | claimed |
| EP-0319482-B1 | Novel substituted propane phosphinic acid compounds | CIBA GEIGY AG (CH) | 1994-05-18 | — | — | EP | claimed |
| EP-0319479-A2 | Substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | claimed |
| EP-0319482-A2 | Novel substituted propane phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | claimed |
| EP-0319482-B1 | Novel substituted propane phosphinic acid compounds | CIBA GEIGY AG (CH) | 1994-05-18 | — | — | EP | disclosed |
| EP-0319479-A2 | Substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |