Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010861 | 0.89 | PPARA (0.58) | PPARGPPARAPPARDHDAC6ALDH1A1 | |
| SCHEMBL6542974 | 0.84 | PPARA (0.51) | PPARGPPARAPPARDHDAC6SMN1; SMN2 | |
| SCHEMBL6542948 | 0.82 | PPARG (0.47) | PPARGPPARAPPARDALDH1A1MAPT | |
| SCHEMBL2441994 | 0.80 | NPC1 (0.39) | HDAC6ELANESMN1; SMN2NPC1RAB9A | |
| SCHEMBL6543351 | 0.79 | PPARA (0.54) | PPARGPPARAPPARDHDAC6ALDH1A1 | |
| SCHEMBL6542946 | 0.76 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL2440537 | 0.76 | PPARG (0.45) | PPARGPPARAPPARDALDH1A1MAPT | |
| SCHEMBL1980682 | 0.75 | BCHE (0.58) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL30583378 | 0.74 | ELANE (0.67) | HDAC6ALDH1A1ELANEMAPTSMN1; SMN2 | |
| SCHEMBL5021495 | 0.74 | ELANE (0.67) | HDAC6ALDH1A1ELANEMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |