Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.51 |
| ▸ | PPARG | P37231 | 10/20 | 0.51 |
| ▸ | PPARD | Q03181 | 5/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436469 | 0.90 | PPARG (0.63) | PPARAPPARGPPARDHDAC6P2RY14 | |
| SCHEMBL6543351 | 0.84 | PPARA (0.54) | PPARAPPARGPPARDHDAC6P2RY14 | |
| SCHEMBL6544189 | 0.84 | PPARG (0.47) | PPARAPPARGPPARDHDAC6NPC1 | |
| SCHEMBL2441994 | 0.82 | NPC1 (0.39) | HDAC6NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL6542975 | 0.78 | PPARA (0.58) | PPARAPPARGPPARDHDAC6P2RY14 | |
| SCHEMBL6543207 | 0.78 | PPARA (0.44) | PPARAPPARGPPARDP2RY14SMN1; SMN2 | |
| SCHEMBL6544102 | 0.78 | PPARA (0.44) | PPARAPPARGPPARDP2RY14TP53 | |
| SCHEMBL6544252 | 0.76 | PPARG (0.62) | PPARAPPARGPPARDMTNR1AMTNR1B | |
| SCHEMBL6542948 | 0.76 | PPARG (0.47) | PPARAPPARGPPARDMTNR1AMTNR1B | |
| SCHEMBL2441085 | 0.76 | PPARA (0.64) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |