Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 5/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2441903 | 0.89 | PPARG (0.43) | NPC1RAB9ATP53SMN1; SMN2ELANE | |
| SCHEMBL1010511 | 0.83 | HDAC6 (0.43) | NPC1RAB9ATP53SMN1; SMN2ELANE | |
| SCHEMBL6542974 | 0.82 | PPARA (0.51) | NPC1RAB9ATP53SMN1; SMN2HDAC6 | |
| SCHEMBL6544189 | 0.80 | PPARG (0.47) | NPC1RAB9ATP53SMN1; SMN2ELANE | |
| SCHEMBL2441990 | 0.78 | PTPN1 (0.35) | NPC1RAB9ASMN1; SMN2ELANE | |
| SCHEMBL2472594 | 0.77 | PPARG (0.60) | TP53ELANENPSR1HSD17B10 | |
| SCHEMBL6543921 | 0.74 | MTNR1A (0.43) | NPC1RAB9ATP53HSD17B10 | |
| SCHEMBL1980682 | 0.74 | BCHE (0.58) | NPC1RAB9ATP53SMN1; SMN2PCSK9 | |
| SCHEMBL2438493 | 0.73 | TAAR1 (0.40) | NPSR1HSD17B10 | |
| SCHEMBL6543415 | 0.72 | PPARG (0.42) | NPC1RAB9ATP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |