Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543660 | 0.87 | ESRRA (0.37) | ABL1BRD4 | |
| SCHEMBL6543097 | 0.87 | PGR (0.33) | ABL1 | |
| SCHEMBL6544812 | 0.84 | ESRRA (0.33) | ABL1 | |
| SCHEMBL28786462 | 0.84 | CARM1 (0.37) | ABL1 | |
| SCHEMBL27782470 | 0.84 | HPGD (0.39) | — | |
| SCHEMBL6543795 | 0.84 | AR (0.36) | BRD4 | |
| SCHEMBL27782482 | 0.83 | ABL1 (0.37) | ABL1 | |
| SCHEMBL6544015 | 0.83 | ALDH1A1 (0.34) | — | |
| SCHEMBL27939698 | 0.82 | KMT2A (0.37) | ABL1BRD4 | |
| SCHEMBL15930785 | 0.81 | ABL1 (0.35) | ABL1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022272-B1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | SANKYO CO (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-6432993-B1 | BENZIMIDAZOLE OR IMIDAZO(4,5-B)PYRIDINE DERIVATES; IMMUNOMODULATORS; ALDOSE REDUCTASE AND LIPOXYGENASE INHIBITORS; DIABETES; PREVENTS LIPID PEROXIDATION; ANTILIPEMIC, HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 2002-08-13 | — | — | US | disclosed |
| EP-1022272-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | Sankyo Company Limited (JP) | 2000-07-26 | — | — | EP | disclosed |