Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27529943 | 0.94 | FFAR3 (0.41) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetone SCHEMBL10400055 | 0.90 | ALDH1A1 (0.43) | FFAR3ALDH1A1TSHRTDP1LMNA | |
| Acetone SCHEMBL27651154 | 0.87 | ALDH1A1 (0.40) | FFAR3ALDH1A1TSHRTDP1LMNA | |
| Acetone SCHEMBL28255139 | 0.87 | ALDH1A1 (0.40) | FFAR3ALDH1A1TSHRTDP1LMNA | |
| Acetic Acid SCHEMBL15689725 | 0.86 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL694363 | 0.86 | — | — | |
| Acetic Acid SCHEMBL3295221 | 0.86 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL3359645 | 0.86 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL15285365 | 0.86 | FFAR3 (0.64) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetic Acid SCHEMBL36929 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116196363-A | Traditional Chinese medicine composition for treating viral pneumonia and preparation method thereof | 四川省中医药科学院 | 2023-06-02 | — | — | CN | disclosed |
| US-20170143837-A1 | COMPOSITION FOR SKIN PENETRATION, CONTAINING CATIONIC MOLECULE TRANSPORTER AND ANIONIC BIOACTIVE MATERIAL | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-05-25 | — | — | US | disclosed |
| US-20160011175-A1 | Methods for Identifying Stem Cells by Detecting Fluorescence of Cells and Syncytia | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2016-01-14 | — | — | US | disclosed |
| US-8940500-B2 | Methods for identifying stem cells by detecting fluorescence of cells and syncytia | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-01-27 | — | — | US | disclosed |
| US-8629323-B2 | Methods and materials for making and using transgenic dicamba-degrading organisms | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2014-01-14 | — | — | US | disclosed |
| US-20120151630-A1 | METHODS AND MATERIALS FOR MAKING AND USING TRANSGENIC DICAMBA-DEGRADING ORGANISMS | BOARD OF REGENTS OF UNIVERSITY OF NEBRASKA (US) | 2012-06-14 | — | — | US | disclosed |
| US-8119380-B2 | Methods and materials for making and using transgenic dicamba-degrading organisms | BOARD OF REGENTS OF UNIVERSITY OF NEBRASKA (US) | 2012-02-21 | — | — | US | disclosed |
| EP-2325308-A2 | Methods and materials for making and using transgenic dicamba-degrading organisms | The Board of Regents of the University of Nebraska (US) | 2011-05-25 | — | — | EP | disclosed |
| US-20110061137-A1 | METHODS AND MATERIALS FOR MAKING AND USING TRANSGENIC DICAMBA-DEGRADING ORGANISMS | BOARD OF REGENTS OF UNIVERSITY OF NEBRASKA (US) | 2011-03-10 | — | — | US | disclosed |
| US-7812224-B2 | Methods and materials for making and using transgenic dicamba-degrading organisms | BOARD OF REGENTS OF UNIVERSITY OF NEBRASKA (US) | 2010-10-12 | — | — | US | disclosed |
| EP-0040494-B1 | CARBAPENAMS AND CARBAPEN-2-EMS AND PROCESS THEREFOR | PFIZER INC. (US) | 1984-02-15 | — | — | EP | disclosed |
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4425333-A | HYPOTENSIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| US-4409141-A | Peptides for assaying human parathyroid hormone | TOYO JOZO KABUSHIKI KAISHA (JP) | 1983-10-11 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0048763-A1 | SULFUR-CONTAINING ACYLAMINO ACIDS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | disclosed |
| US-4179451-A | HYPOTENSIVE, ANTIULCER, BRONCHODILATOR, ANTICONVULSANTS OR ANTIMICROBIAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4107441-A | HYPOTENSIVE, ANTIULCER, BRONCHODILATORS, ANTIMICROBIAL, ANTICONVULSANTS | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4001279-A | CARRY INSOLUBLE REAGENT SUBSTANCES INTO SOLUTION IN NON-HYDROXYLIC MEDIA; CROWN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170143837-A1 | COMPOSITION FOR SKIN PENETRATION, CONTAINING CATIONIC MOLECULE TRANSPORTER AND ANIONIC BIOACTIVE MATERIAL | SLCO4C1, SLCO2B1, SLC22A8 | FFAR3 572/4885LCK 3810/4885FYN 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.