Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544747 | 0.78 | GPR3 (0.34) | GPR3HTR2APOLB | |
| SCHEMBL2882645 | 0.74 | GPR3 (0.41) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL29130722 | 0.74 | GPR3 (0.41) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL30360122 | 0.74 | GPR3 (0.41) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL5573163 | 0.73 | GPR3 (0.41) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL6544336 | 0.73 | GPR3 (0.41) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL29162234 | 0.73 | MAOA (0.52) | HTR2AKMT2AMEN1ATMHDAC3 | |
| SCHEMBL2545663 | 0.73 | GPR3 (0.41) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL2547987 | 0.70 | ACHE (0.39) | GPR3HTR2APOLBACHECHRM2 | |
| SCHEMBL14476649 | 0.70 | GPR3 (0.38) | GPR3HTR2APOLBACHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373284-A1 | CATALYSTS CHARACTERIZED BY A DONOR-ACCEPTOR INTERACTION | Bayer Aktiengesellschaft (DE) | 2004-01-02 | — | — | EP | disclosed |
| US-6657027-B2 | Compounds in which a transition metal is complexed with two ligand systems that systems are reversibly bonded together by a bridge ofa donor and an acceptor; at least one fluorinated aryl radical; olefin polymerization catalysts | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-02 | — | — | US | disclosed |
| US-20030036474-A1 | Catalysts with a donor-acceptor interaction | LANXESS DEUTSCHLAND GMBH (DE) | 2003-02-20 | — | — | US | disclosed |
| WO-2002076999-A1 | CATALYSTS CHARACTERIZED BY A DONOR-ACCEPTOR INTERACTION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-03 | — | — | WO | disclosed |
| EP-0568007-B1 | Electrophotographic photoreceptor | MITSUBISHI CHEM CORP (JP) | 1997-02-26 | — | — | EP | disclosed |
| US-5389481-A | Using substrate made electroconductive by inclusion of low molecular weight arylamine compounds | MITSUBISHI KASEI CORPORATION (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0568007-A1 | Electrophotographic photoreceptor | Mitsubishi Chemical Corporation (JP) | 1993-11-03 | — | — | EP | disclosed |