SCHEMBL6544620

SCHEMBL6544620

C[N+](C)(C)CCC[Si](O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
ACHE P22303 4/20 0.47
APEX1 P27695 3/20 0.47
NFKB1 P19838 2/20 0.47
KDM4E B2RXH2 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
PMP22 Q01453 2/20 0.47
LMNA P02545 2/20 0.47
HSD17B10 Q99714 1/20 0.47
HRH3 Q9Y5N1 1/20 0.47
TSHR P16473 1/20 0.47
RAB9A P51151 1/20 0.47
NPSR1 Q6W5P4 1/20 0.45
DNM1 Q05193 6/20 0.39
BBOX1 O75936 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6544618 0.97 APEX1 (0.50) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL12173199 0.81 MEN1 (0.53) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL19929624 0.76 MEN1 (0.41) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL12173197 0.73 MEN1 (0.50) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL19929621 0.72 MEN1 (0.38) MEN1KMT2AACHEAPEX1NFKB1
Hydrochloric Acid SCHEMBL7205565 0.72 APEX1 (0.48) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL2715248 0.71 HTT (0.65) KMT2ALMNADNM1
SCHEMBL17256642 0.71 HTT (0.65) KMT2ALMNADNM1
Hydrochloric Acid SCHEMBL6046691 0.71 APEX1 (0.53) MEN1KMT2AACHEAPEX1NFKB1
Iodide SCHEMBL22263021 0.69 HTT (0.62) KMT2ALMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1082223-B1 IMAGING AND PRINTING METHODS USING CLAY-CONTAINING FLUID RECEIVING ELEMENT KODAK POLYCHROME GRAPHICS CO (US) 2004-01-07 EP claimed
US-10258046-B2 Antimicrobial coatings comprising quaternary silanes ALLIED BIOSCIENCE, INC. (US) 2019-04-16 US disclosed
US-10238114-B2 Methods of preparing reactive mixtures of silanes and triethanolamine and polymers therefrom SRFC BIO, INC. 2019-03-26 US disclosed
US-10194664-B2 Methods of preparing self-decontaminating surfaces using reactive silanes, triethanolamine and titanium anatase sol ALLIED BIOSCIENCE, INC. (US) 2019-02-05 US disclosed
US-9963596-B2 Synergistic combinations of choline and reactive silanes in antimicrobial coatings ALLIED BIOSCIENCE, INC. (US) 2018-05-08 US disclosed
US-9918475-B2 Anti-microbial coating and method to form same ALLIED BIOSCIENCE, INC. (US) 2018-03-20 US disclosed
US-20170166755-A1 SYNERGISTIC COMBINATIONS OF CHOLINE AND REACTIVE SILANES IN ANTIMICROBIAL COATINGS ALLIED BIOSCIENCE, INC. (US) 2017-06-15 US disclosed
US-20170152401-A1 METHODS OF PREPARING REACTIVE MIXTURES OF SILANES AND TRIETHANOLAMINE AND POLYMERS THEREFROM ALLIED BIOSCIENCE, INC. (US) 2017-06-01 US disclosed
US-20170150723-A1 METHODS OF PREPARING SELF-DECONTAMINATING SURFACES USING REACTIVE SILANES, TRIETHANOLAMINE AND TITANIUM ANATASE SOL ALLIED BIOSCIENCE, INC. (US) 2017-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10194664-B2 Methods of preparing self-decontaminating surfaces using reactive silanes, triethanolamine and titanium anatase sol PHOSPHO1, SAT1, SEPTIN8 MEN1 2337/4885KMT2A 423/4885ACHE 917/4885
US-10238114-B2 Methods of preparing reactive mixtures of silanes and triethanolamine and polymers therefrom PHOSPHO1, SGMS1, SGMS2 MEN1 2352/4885KMT2A 355/4885ACHE 1002/4885
US-20170152401-A1 METHODS OF PREPARING REACTIVE MIXTURES OF SILANES AND TRIETHANOLAMINE AND POLYMERS THEREFROM PHOSPHO1, SGMS1, SGMS2 MEN1 2352/4885KMT2A 355/4885ACHE 1002/4885
US-20170150723-A1 METHODS OF PREPARING SELF-DECONTAMINATING SURFACES USING REACTIVE SILANES, TRIETHANOLAMINE AND TITANIUM ANATASE SOL PHOSPHO1, SAT1, SEPTIN8 MEN1 2337/4885KMT2A 423/4885ACHE 917/4885
US-10258046-B2 Antimicrobial coatings comprising quaternary silanes TET3, TET2, TET1 MEN1 3151/4885KMT2A 930/4885ACHE 973/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.