Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10391474 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4ELMNAF2 | |
| SCHEMBL7056947 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4ELMNAF2 | |
| SCHEMBL295741 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRKDM4ELMNAF2 | |
| SCHEMBL5828002 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRKDM4EF2MMP8 | |
| SCHEMBL9420589 | 0.84 | KCNA5 (0.47) | ALDH1A1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL2512047 | 0.81 | CYP3A4 (0.49) | ALDH1A1KDM4ELMNAMMP8CYP3A4 | |
| SCHEMBL28906659 | 0.81 | MDM4 (0.45) | ALDH1A1TSHRLMNAF2MMP8 | |
| SCHEMBL6545363 | 0.80 | RIPK1 (0.46) | LMNANPC1 | |
| SCHEMBL7178642 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRLMNAF2MMP8 | |
| SCHEMBL27466587 | 0.79 | CYP3A4 (0.54) | ALDH1A1KDM4ELMNAMMP8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812368-B2 | CATALYTIC HYDROGENATION USING MAGNESIUM COMPOUND AND PLATINUM | SOLVIAS AG (CH) | 2004-11-02 | — | — | US | disclosed |
| US-20040010154-A1 | Diastereoselective hydrogenation of 1,3-hydroxyketones | SOLVIAS AG (CH) | 2004-01-15 | — | — | US | disclosed |
| EP-1378501-A1 | Diastereoselective hydrogenation of beta-hydroxyketones | Solvias AG (CH) | 2004-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010154-A1 | Diastereoselective hydrogenation of 1,3-hydroxyketones | HK1, HSD17B7, GRIK1 | ALDH1A1 274/4885TSHR 3575/4885KDM4E 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.