Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 9/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544302 | 0.86 | PTGS2 (0.48) | — | |
| SCHEMBL6697832 | 0.85 | SCN10A (0.38) | MEN1KMT2AHTTSCN10ACYP1A2 | |
| SCHEMBL6699629 | 0.84 | SCN10A (0.37) | MEN1KMT2ASCN10ACYP1A2LMNA | |
| SCHEMBL6697827 | 0.83 | ALDH1A1 (0.35) | MEN1KMT2AHTTSCN10ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6700556 | 0.83 | SCN10A (0.36) | MEN1KMT2ASCN10ACYP1A2LMNA | |
| SCHEMBL6699623 | 0.81 | CYP1A2 (0.35) | MEN1KMT2AHTTSCN10ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6700552 | 0.81 | MEN1 (0.35) | MEN1KMT2AHTTSCN10ACYP1A2 | |
| SCHEMBL6543663 | 0.80 | PPARG (0.43) | — | |
| Hydrochloric Acid SCHEMBL6544226 | 0.79 | PPARG (0.43) | — | |
| SCHEMBL6701382 | 0.77 | PPARA (0.35) | MEN1KMT2ACYP1A2LMNANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022272-B1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | SANKYO CO (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-6432993-B1 | BENZIMIDAZOLE OR IMIDAZO(4,5-B)PYRIDINE DERIVATES; IMMUNOMODULATORS; ALDOSE REDUCTASE AND LIPOXYGENASE INHIBITORS; DIABETES; PREVENTS LIPID PEROXIDATION; ANTILIPEMIC, HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 2002-08-13 | — | — | US | disclosed |
| EP-1022272-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | Sankyo Company Limited (JP) | 2000-07-26 | — | — | EP | disclosed |