Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 12/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.36 |
| ▸ | LIPC | P11150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805636 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL25261185 | 0.93 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL7814936 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTTDP1HTT | |
| SCHEMBL7078416 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTTDP1HTT | |
| SCHEMBL31480867 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL25243349 | 0.80 | MAPT (0.38) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL25243350 | 0.80 | MAPT (0.38) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL7956455 | 0.80 | ROCK2 (0.37) | ACACBLIPG | |
| SCHEMBL7807712 | 0.77 | CALML3 (0.51) | LMNA | |
| SCHEMBL7807715 | 0.77 | CALML3 (0.51) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | L'OREAL S.A. (FR) | 2004-04-01 | — | — | US | claimed |
| EP-1375480-A1 | Para-phenylene-diamine derivatives comprising a silyl substituted pyrrolidine group and their use for the colouring of keratinic fibres | L'OREAL (FR) | 2004-01-02 | — | — | EP | claimed |
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | L'OREAL S.A. (FR) | 2004-04-01 | — | — | US | disclosed |
| EP-1375480-A1 | Para-phenylene-diamine derivatives comprising a silyl substituted pyrrolidine group and their use for the colouring of keratinic fibres | L'OREAL (FR) | 2004-01-02 | — | — | EP | disclosed |
| EP-1375480-A1 | Para-phenylene-diamine derivatives comprising a silyl substituted pyrrolidine group and their use for the colouring of keratinic fibres | L'OREAL (FR) | 2004-01-02 | — | — | EP | disclosed |
| US-6617339-B1 | 5-Isoxazolyloxymethyl-3-((dihydroxypropanoyl)-4-tetrahydropyri dyl-3,5- difluorophenyl)oxazolidinone, or the phosphated derivative or its disodium salt; antibiotic with useful activity against Grampositive pathogens | SYNGENTA LIMITED (GB) | 2003-09-09 | — | — | US | disclosed |
| US-20030144263-A1 | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | SYNGENTA LIMITED (GB) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | KRT18, VIM, CDC73 | ALDH1A1 785/4885LMNA 188/4885MAPT 1037/4885 |
| US-20030144263-A1 | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | CYP3A5, CYP2D6, OXA1L | ALDH1A1 3134/4885LMNA 3058/4885MAPT 4796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.