Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953203 | 0.84 | MAPK1 (0.53) | ALDH1A1ALOX12MAPK1GAA | |
| SCHEMBL4846520 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TSHRKDM4ECYP1A2ALOX12 | |
| SCHEMBL8502739 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TSHRKDM4ECYP1A2ALOX12 | |
| SCHEMBL9049892 | 0.79 | ALDH1A1 (0.33) | ALDH1A1ALOX12MAPK1 | |
| SCHEMBL9049885 | 0.79 | ALDH1A1 (0.33) | ALDH1A1ALOX12MAPK1 | |
| SCHEMBL11062607 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TSHRKDM4ECYP1A2HIF1A | |
| SCHEMBL6545133 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRKDM4EALOX12RAB9A | |
| SCHEMBL10975655 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP1A2HIF1AALOX12 | |
| SCHEMBL31405426 | 0.75 | BRD4 (0.39) | ALDH1A1CYP1A2HIF1AALOX12BRD4 | |
| SCHEMBL1577521 | 0.74 | ALDH1A1 (0.51) | ALDH1A1TSHRKDM4ECYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332729-B | Preparation method of 3, 5-dihydroxytoluene | 厦门沃克沃德医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116332729-A | Preparation method of 3, 5-dihydroxytoluene | 厦门沃克沃德医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |
| EP-1027055-B1 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4(10H)-ONE DERIVATIVES | UNIV HOWARD (US) | 2004-01-07 | — | — | EP | disclosed |
| US-20030149293-A1 | Method for producing 1,3-cyclohexanediol compound | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-08-07 | — | — | US | disclosed |
| EP-1333019-A1 | Method for producing 1,3-cyclohexanediol compound | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-1027055-A4 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4(10H)-ONE DERIVATIVES | UNIV HOWARD (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-1027055-A1 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4(10H)-ONE DERIVATIVES | HOWARD UNIVERSITY (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5994349-A | ANTIEPILEPTIC AGENTS | HOWARD UNIVERSITY (US) | 1999-11-30 | — | — | US | disclosed |
| WO-1999021560-A1 | 3-CARBOALKOXY-2,3-DIHYDRO-1H-PHENOTHIAZIN-4[10H]-ONE DERIVATIVES | HOWARD UNIVERSITY (US) | 1999-05-06 | — | — | WO | disclosed |
| US-5580894-A | NERVOUS SYSTEM DISORDERS | HOWARD UNIVERSITY (US) | 1996-12-03 | — | — | US | disclosed |
| US-4607120-A | A OMATIZATION | SOCIETE ANONYME ROURE BERTRAND DUPONT (FR) | 1986-08-19 | — | — | US | disclosed |
| US-4432378-A | ORGANOLEPTIC; TOBACCO; FOODS; DETERGENTS; COSMETICS | FRITZSCHE, DODGE & OLCOTT, INC. (US) | 1984-02-21 | — | — | US | disclosed |
| US-4326996-A | FOR PERFUMES | FRITZSCHE DODGE & OLCOTT INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4281204-A | ALKYLATION, DECARBOXYLATION TO CYCLIZE | FRITZSCHE DODGE & OLCOTT INC. (US) | 1981-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149293-A1 | Method for producing 1,3-cyclohexanediol compound | NISCH, HSD11B2, ACMSD | ALDH1A1 1070/4885TSHR 3598/4885KDM4E 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.