Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RARB | P10826 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307985 | 0.85 | ACE (0.47) | HTTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7307992 | 0.85 | ACE (0.47) | HTTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11828127 | 0.83 | MMP12 (0.51) | HTTGAAMMP12MMP13 | |
| SCHEMBL11827920 | 0.83 | PTGS2 (0.49) | ALDH1A1RARBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5373775 | 0.82 | SLC7A5 (0.43) | MMP12MMP13 | |
| SCHEMBL11854668 | 0.76 | BCL2L1 (0.46) | — | |
| SCHEMBL11831427 | 0.76 | MAOB (0.47) | KMT2AMEN1TDP1MMP12HSD17B10 | |
| SCHEMBL14720935 | 0.75 | ALDH1A1 (0.52) | HTTALDH1A1RARBKMT2AMEN1 | |
| SCHEMBL104594 | 0.74 | GRIN2D (0.57) | HTTALDH1A1RARBKMT2AMEN1 | |
| SCHEMBL7438187 | 0.74 | TAAR1 (0.40) | HTTALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377601-A2 | TYPE B BOTULISM TOXIN INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083716-A2 | TYPE B BOTULISM TOXIN INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-10-24 | — | — | WO | disclosed |