Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545442 | 0.94 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL3840808 | 0.91 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL8736122 | 0.90 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL62 | 0.88 | AGTR1 (0.73) | AGTR1AGTR2 | |
| SCHEMBL6546048 | 0.88 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL6545316 | 0.88 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL7443225 | 0.86 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL16327904 | 0.85 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9558459 | 0.85 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL317 | 0.85 | AGTR1 (0.55) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561977-B1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE TREATMENT OF HEMORRAGIC STROKE | SMITHKLINE BEECHAM PLC (GB) | 2004-05-26 | — | — | EP | claimed |
| EP-1019048-B1 | USE OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREPARATION OF DRUGS TO INCREASE THE SURVIVAL RATE OF RENAL TRANSPLANT PATIENTS | MERCK SHARP DOHME ITALIA S P A (IT) | 2004-01-21 | — | — | EP | claimed |
| EP-0724387-B1 | ANGIOTENSION II RECEPTOR ANTAGONISTS FOR THE TREATMENT OF CHRONIC ANTI-INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2003-05-02 | — | — | EP | claimed |
| EP-0324377-B1 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | DU PONT (US) | 1997-04-16 | — | — | EP | claimed |
| EP-0533840-B1 | TREATMENT OF CHRONIC RENAL FAILURE WITH IMIDAZOLE ANGIOTENSIN-II RECEPTOR ANTAGONISTS | DU PONT (US) | 1996-12-11 | — | — | EP | claimed |
| EP-1014989-B1 | ENDOTHELIN ANTAGONIST AND A RENIN-ANGIOTENSIN SYSTEM INHIBITOR AS A COMBINED PREPARATION | ABBOTT GMBH & CO KG (DE) | 2004-01-14 | — | — | EP | disclosed |
| EP-0634175-B1 | Pharmaceutical combination, containing a renin-angiotensin-system inhibitor and an endothelin antagonist | HOFFMANN LA ROCHE (CH) | 2001-01-10 | — | — | EP | disclosed |
| EP-0634175-A1 | Pharmaceutical combination, containing a renin-angiotensin-system inhibitor and an endothelin antagonist | F. HOFFMANN-LA ROCHE AG (CH) | 1995-01-18 | — | — | EP | disclosed |