Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL29129757 | 0.92 | — | — | |
| Glycine SCHEMBL5921139 | 0.89 | — | — | |
| Glycine SCHEMBL6163 | 0.88 | — | — | |
| Glycine SCHEMBL391786 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL391027 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL13169653 | 0.88 | — | — | |
| Glycine SCHEMBL3640989 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL6675874 | 0.88 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL2116443 | 0.88 | — | — | |
| Glycine SCHEMBL93765 | 0.88 | GLRA1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805528-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114591422-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-113181370-A | Synthesis process of tumor targeting drug | 六安市康恒生物科技有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-108026162-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2018-05-11 | — | — | CN | claimed |
| US-9890245-B2 | Stearic acid derivatives and oleic acid derivatives of multi-arm polyethylene glycol | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2018-02-13 | — | — | US | claimed |
| CN-104479126-B | Multi-arm polyethylene glycol stearic acic derivative and oleic acid derivatives | 天津键凯科技有限公司 | 2016-10-05 | — | — | CN | claimed |
| US-20160272762-A1 | STEARIC ACID DERIVATIVES AND OLEIC ACID DERIVATIVES OF MULTI-ARM POLYETHYLENE GLYCOL | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2016-09-22 | — | — | US | claimed |
| CN-103755949-B | Multi-arm polyethylene glycol derivative and with the binding substances of medicine and gel | TIANJIN JENKEM TECHNOLOGY CO., LTD. (CN) | 2016-04-13 | — | — | CN | claimed |
| CN-104479126-A | Dobby polyethylene glycol stearic acid derivative and oleic acid derivative | TIANJIN JENKEM TECHNOLOGY CO LTD | 2015-04-01 | — | — | CN | claimed |
| CN-103755949-A | Dobby polyethylene glycol derivative and conjugate thereof with drug and gel | TIANJIN JENKEM TECHNOLOGY CO LTD | 2014-04-30 | — | — | CN | claimed |
| US-3965350-A | Dye penetrant method for detecting flows | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1976-06-22 | — | — | US | claimed |
| CN-114591422-B | Cystine knot support platform | 豪夫迈·罗氏有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-118345256-A | Gallium extractant, preparation thereof and application thereof in gallium extraction | 深圳市中金岭南有色金属股份有限公司丹霞冶炼厂 | 2024-07-16 | — | — | CN | disclosed |
| CN-112415508-B | Determining a mixing ratio | 西门子瑞士有限公司 | 2024-07-09 | — | — | CN | disclosed |
| US-11614425-B2 | Determination of the mixing ratio in particular of a water/glycol mixture by means of ultrasound and a heat flow measurement based thereon | SIEMENS SCHWEIZ AG (CH) | 2023-03-28 | — | — | US | disclosed |
| CN-104479126-A | Dobby polyethylene glycol stearic acid derivative and oleic acid derivative | TIANJIN JENKEM TECHNOLOGY CO LTD | 2015-04-01 | — | — | CN | disclosed |
| US-20140117280-A1 | OXYGEN ABSORBER | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-05-01 | — | — | US | disclosed |
| CN-103755949-A | Dobby polyethylene glycol derivative and conjugate thereof with drug and gel | TIANJIN JENKEM TECHNOLOGY CO LTD | 2014-04-30 | — | — | CN | disclosed |
| EP-1379595-A2 | DISPERSIONS | Avecia Limited (GB) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002062905-A2 | DISPERSIONS | AVECIA LIMITED (GB) | 2002-08-15 | — | — | WO | disclosed |