Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 3/20 | 0.36 |
| ▸ | CD14 | P08571 | 3/20 | 0.36 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 5/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CD69 | Q07108 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2369331 | 0.89 | TLR4 (0.34) | TLR4CD14LY96 | |
| SCHEMBL8633940 | 0.74 | ELANE (0.35) | TLR4CD14LY96ELANECD69 | |
| SCHEMBL8907901 | 0.73 | CNR1 (0.37) | — | |
| SCHEMBL5051084 | 0.71 | TLR4 (0.35) | TLR4CD14LY96RXRARXRB | |
| SCHEMBL6435626 | 0.71 | TLR4 (0.35) | TLR4CD14LY96RXRARXRB | |
| SCHEMBL6431828 | 0.71 | TLR4 (0.35) | TLR4CD14LY96RXRARXRB | |
| SCHEMBL5048789 | 0.71 | TLR4 (0.35) | TLR4CD14LY96RXRARXRB | |
| SCHEMBL14533611 | 0.71 | TLR4 (0.35) | TLR4CD14LY96RXRARXRB | |
| SCHEMBL1531365 | 0.71 | TLR4 (0.35) | TLR4CD14LY96RXRARXRB | |
| SCHEMBL98164 | 0.71 | TLR4 (0.35) | TLR4CD14LY96RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377564-A2 | TRANSITION-METAL-CATALYZED PROCESS FOR THE PREPARATION OF STERICALLY HINDERED N-SUBSTITUTED ALKOXYAMINES | Ciba SC Holding AG (CH) | 2004-01-07 | — | — | EP | disclosed |
| EP-1353959-A1 | SURFACE-ACTIVE PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2003-10-22 | — | — | EP | disclosed |
| EP-1349877-A1 | SURFACE-ACTIVE PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2003-10-08 | — | — | EP | disclosed |
| EP-1341823-A1 | SURFACE-ACTIVE PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002079182-A2 | TRANSITION-METAL-CATALYZED PROCESS FOR THE PREPARATION OF STERICALLY HINDERED N-SUBSTITUTED ALKOXYAMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | disclosed |
| WO-2002048203-A1 | SURFACE-ACTIVE PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | disclosed |
| WO-2002048202-A1 | SURFACE-ACTIVE PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | disclosed |
| WO-2002048204-A1 | SURFACE-ACTIVE PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | disclosed |