SCHEMBL8633940

SCHEMBL8633940

CC(C)(C)c1cc2c(c(C(C)(C)C)c1)OPOc1c(cc(C(C)(C)C)cc1C(C)(C)C)C2

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.35
CD69 Q07108 1/20 0.35
GABBR2 O75899 1/20 0.35
GABBR1 Q9UBS5 1/20 0.35
TLR4 O00206 3/20 0.31
CD14 P08571 3/20 0.31
LY96 Q9Y6Y9 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8631061 0.82 SMN1; SMN2 (0.39)
SCHEMBL19648626 0.80 ELANE (0.36) ELANECD69GABBR2GABBR1TLR4
SCHEMBL8907901 0.80 CNR1 (0.37)
SCHEMBL10712732 0.79 ELANE (0.35) ELANECD69GABBR2GABBR1TLR4
SCHEMBL10710936 0.79 ELANE (0.35) ELANECD69GABBR2GABBR1TLR4
SCHEMBL8908019 0.78 CA1 (0.44)
SCHEMBL8633313 0.78 HSPA5 (0.39)
SCHEMBL24882702 0.77 ELANE (0.34) ELANECD69GABBR2GABBR1TLR4
SCHEMBL25671804 0.77 ELANE (0.34) ELANECD69GABBR2GABBR1TLR4
SCHEMBL4440720 0.76 GABBR2 (0.36) ELANECD69GABBR2GABBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210246256-A1 POLYURETHANE FOAM OR POLYETHER POLYOL STABILIZED WITH A BENZOFURANONE-PHOSPHITE DERIVATIVE BASF SE (DE) 2021-08-12 US disclosed
WO-2021110852-A1 FLAME RETARDANT POLYMER COMPRISING PHOSPHORUS-CONTAINING REPEATING UNITS, PLASTIC COMPOSITION COMPRISING THE FLAME RETARDANT POLYMER, PROCESS FOR PRODUCING THE FLAME RETARDANT POLYMER AND USE THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2021-06-10 WO disclosed
US-10941285-B2 Stabilized polyolefin compositions comprising benzofuranones and acid scavengers BASF SE (DE) 2021-03-09 US disclosed
EP-3728473-A1 USE OF POLYAMIDE MOLDING COMPOUNDS TO REDUCE COATING FORMATION IN THERMOPLASTIC PROCESSING, POLYAMIDE MOLDING COMPOUND AND METHOD FOR PRODUCING USEFUL OBJECTS EMS-Patent AG (CH) 2020-10-28 EP disclosed
EP-2652031-A1 COLOUR-STABLE LED SUBSTRATES Bayer Intellectual Property GmbH (DE) 2013-10-23 EP disclosed
WO-2012080396-A1 COLOUR-STABLE LED SUBSTRATES BAYER MATERIALSCIENCE AG (DE) 2012-06-21 WO disclosed
US-5712403-A CATALYST MITSUBISHI CHEMICAL CORPORATION (JP) 1998-01-27 US disclosed
US-5600032-A OLIGOMERIZATION OF A CONJUGATED ALKADIENE IN PRESENCE OFPALLADIUM, PHOSPHORUS COMPLEX MITSUBISHI CHEMICAL CORPORATION (JP) 1997-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10941285-B2 Stabilized polyolefin compositions comprising benzofuranones and acid scavengers PUF60, PCBP1, MORF4L1 ELANE 3221/4885CD69 3430/4885GABBR2 1285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.