Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755331 | 0.95 | ALDH1A1 (0.49) | ABCB1ALDH1A1 | |
| SCHEMBL6545613 | 0.91 | ABCB1 (0.47) | ABCB1ALDH1A1 | |
| SCHEMBL6546452 | 0.89 | ABCB1 (0.52) | ABCB1ALDH1A1 | |
| SCHEMBL6545874 | 0.86 | ABCB1 (0.46) | ABCB1 | |
| SCHEMBL2226912 | 0.81 | ABCB1 (0.58) | ABCB1 | |
| SCHEMBL12919766 | 0.77 | ALDH1A1 (0.62) | ALDH1A1 | |
| SCHEMBL7051488 | 0.74 | APP (0.47) | ABCB1 | |
| SCHEMBL8724093 | 0.72 | PSMB11 (0.71) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8979987 | 0.71 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7753317 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257265-B1 | USE OF 2-PHENYLENE DIAMINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | BIOAGENCY AG (DE) | 2004-01-21 | — | — | EP | disclosed |
| US-20030036532-A1 | Use of 2-phenylene diamine derivatives for the treatment of infections | JOMAA PHARMAKA GMBH (DE) | 2003-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036532-A1 | Use of 2-phenylene diamine derivatives for the treatment of infections | HRH2, ASPH, NQO2 | ABCB1 245/4885MEN1 3863/4885KMT2A 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.