Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545613 | 0.96 | ABCB1 (0.47) | ALDH1A1LMNAABCB1 | |
| SCHEMBL6545867 | 0.95 | ABCB1 (0.50) | ALDH1A1ABCB1 | |
| SCHEMBL6546452 | 0.95 | ABCB1 (0.52) | ALDH1A1ABCB1 | |
| SCHEMBL6545874 | 0.92 | ABCB1 (0.46) | ABCB1 | |
| SCHEMBL2226912 | 0.85 | ABCB1 (0.58) | ABCB1 | |
| SCHEMBL12919766 | 0.74 | ALDH1A1 (0.62) | ALDH1A1LMNA | |
| SCHEMBL6546175 | 0.74 | PKM (0.55) | ALDH1A1LMNA | |
| SCHEMBL7051490 | 0.72 | ABCB1 (0.44) | ABCB1 | |
| SCHEMBL7051491 | 0.72 | ABCB1 (0.44) | ABCB1 | |
| SCHEMBL18655903 | 0.71 | LTB4R (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068176-A1 | CYSTEINE AMIDES AS FARNESYL TRANSFERASE INHIBITORS | Jomaa, Hassan (DE) | 2001-01-17 | — | — | EP | disclosed |
| WO-2000027803-A1 | CYSTEINE AMIDES AS FARNESYL TRANSFERASE INHIBITORS | JOMAA, HASSAN (DE) | 2000-05-18 | — | — | WO | disclosed |