SCHEMBL6546081

SCHEMBL6546081

CCCc1ccccc1C(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
TYR P14679 1/20 0.41
SLC6A4 P31645 1/20 0.40
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
CYSLTR2 Q9NS75 7/20 0.38
CYSLTR1 Q9Y271 7/20 0.38
TAAR1 Q96RJ0 2/20 0.36
HTT P42858 1/20 0.36
LMNA P02545 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10602405 0.96 ADRA2A (0.40) ADRA2AADRA2BADRA2CTYRSLC6A4
SCHEMBL6547601 0.89 CYSLTR2 (0.46) TYRSLC6A4CYSLTR2CYSLTR1CYP2C9
SCHEMBL9621039 0.88 ADRA2A (0.46) ADRA2AADRA2BADRA2CSLC6A4CYSLTR2
SCHEMBL23285181 0.86 SLC6A4 (0.39) ADRA2AADRA2BADRA2CSLC6A4KMT2A
SCHEMBL28674805 0.84 HTT (0.45) TYRSLC6A4TAAR1HTTLMNA
SCHEMBL3074943 0.84 HTT (0.45) TYRSLC6A4TAAR1HTTLMNA
SCHEMBL29486474 0.84 HTT (0.45) TYRSLC6A4TAAR1HTTLMNA
SCHEMBL11205190 0.83 HTR1A (0.41) TYRSLC6A4KMT2A
SCHEMBL6547900 0.82 HTR2A (0.42) ADRA2AADRA2BADRA2CPPARGPPARA
SCHEMBL10601615 0.81 HTT (0.43) TYRSLC6A4TAAR1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0047998-B1 ELECTRICALLY INSULATING OIL COMPOSITION Nippon Petrochemicals Co., Ltd. (JP) 1985-08-07 EP disclosed
US-4442027-A Electrical insulating oil composition NIPPON PETROCHEMICALS COMPANY LTD. (JP) 1984-04-10 US disclosed
EP-0047998-A1 Electrically insulating oil composition Nippon Petrochemicals Co., Ltd. (JP) 1982-03-24 EP disclosed